Two phases of increased cell death in the inner retina following early elimination of the ganglion cell population

  title={Two phases of increased cell death in the inner retina following early elimination of the ganglion cell population},
  author={K. Cusato and S. B. Stagg and B. Reese},
  journal={Journal of Comparative Neurology},
  • K. Cusato, S. B. Stagg, B. Reese
  • Published 2001
  • Biology, Medicine
  • Journal of Comparative Neurology
  • Neurons in the inner nuclear layer (INL) of the vertebrate retina undergo considerable programmed cell death during development, but the determinants of this cell death remain largely unknown. The present study examines the role of retinal ganglion cells in support of INL neurons in the developing ferret retina. The retinal ganglion cell population was eliminated by optic nerve transection at postnatal day (P) 2, and the incidence of cell death was examined using terminal deoxytransferase dUTP… CONTINUE READING
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