Two perspectives on the twist of DNA.

@article{Britton2009TwoPO,
  title={Two perspectives on the twist of DNA.},
  author={Lauren A Britton and Wilma K. Olson and Irwin Tobias},
  journal={The Journal of chemical physics},
  year={2009},
  volume={131 24},
  pages={245101}
}
Because of the double-helical structure of DNA, in which two strands of complementary nucleotides intertwine around each other, a covalently closed DNA molecule with no interruptions in either strand can be viewed as two interlocked single-stranded rings. Two closed space curves have long been known by mathematicians to exhibit a property called the linking number, a topologically invariant integer, expressible as the sum of two other quantities, the twist of one of the curves about the other… CONTINUE READING

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