Two-peaked increase of serum myosin heavy chain-α after triathlon suggests heart muscle cell death

@article{Danielsson2019TwopeakedIO,
  title={Two-peaked increase of serum myosin heavy chain-$\alpha$ after triathlon suggests heart muscle cell death},
  author={T. Danielsson and Hendrik Schreyer and H. Woksepp and Ther{\'e}se Johansson and P. Bergman and A. M{\aa}nsson and J. Carlsson},
  journal={BMJ Open Sport — Exercise Medicine},
  year={2019},
  volume={5}
}
Objective It has been suggested that the mechanism behind cardiac troponin elevation after strenuous exercise is passage through a cell membrane with changed permeability rather than myocardial cell death. We hypothesised that an increase of cardiac specific myosin heavy chain-alpha (MHC-α; 224 kDa compared with cardiac troponin T’s (cTnT) 37 kDa) could hardly be explained by passage through a cell membrane. Methods Blood samples were collected from 56 athletes (15 female, age 42.5±9.7, range… Expand

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