Two pathways of apoptosis are simultaneously induced in the embryonal brains of neural cell-specific HIF-1α-deficient mice

Abstract

The aim of this study was to clarify the mechanism of apoptosis seen in the cortex of neural cell-specific hypoxia inducible factor-1α (HIF-1α)-deficient embryos. A previous study showed that the neural cells in the cortical area of the mutant embryos underwent apoptosis coincident with vascular regression. Through histological, immunohistochemical, and… (More)
DOI: 10.1007/s00418-005-0101-1

Topics

6 Figures and Tables

Cite this paper

@article{Ueno2005TwoPO, title={Two pathways of apoptosis are simultaneously induced in the embryonal brains of neural cell-specific HIF-1α-deficient mice}, author={Masaki Ueno and Shuhei Tomita and Masaaki Ueki and Yasuyuki Iwanaga and Cheng-long Huang and Masayuki Onodera and Nobuhiro Maekawa and Frank J. Gonzalez and Haruhiko Sakamoto}, journal={Histochemistry and Cell Biology}, year={2005}, volume={125}, pages={535-544} }