Two olfactory marker proteins in Xenopus laevis
@article{Roessler1998TwoOM, title={Two olfactory marker proteins in Xenopus laevis}, author={Patricia Roessler and Mario Mezler and Heinz Breer}, journal={Journal of Comparative Neurology}, year={1998}, volume={395} }
Mature olfactory receptor neurons of mammals are characterized by the expression of the highly conserved olfactory marker protein (OMP) encoded by single copy genes. In Xenopus laevis, two homologous genes encoding olfactory marker proteins have been identified that share a sequence identity with mammalian OMPs of about 50%. Sequence comparison revealed significant variability in the N‐terminus and C‐terminus regions; in contrast, two internal domains were highly conserved between amphibian and…
20 Citations
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Using RT-PCR and in situ hybridization, it was found that expression of Xenopus olfactory marker protein and of class I receptors, which are thought to be responsible for the perception of water-soluble odorants, was detectable as early as stage 32, less than 2 days after fertilization.
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- BiologyProceedings of the National Academy of Sciences
- 2013
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