Two novel SCN1A mutations identified in families with familial hemiplegic migraine.

@article{Weller2014TwoNS,
  title={Two novel SCN1A mutations identified in families with familial hemiplegic migraine.},
  author={C. M. Kellett S. R. Weller and Nadine Pelzer and Boukje de Vries and Merc{\`e} Artigas L{\'o}pez and Oriol De Fabregues and Julio Pascual and Maria Antonia Ramos Arroyo and Stephany C. Koelewijn and Anine H. Stam and Joost Haan and Michel D. Ferrari and Gisela M. Terwindt and Arn M J M van den Maagdenberg},
  journal={Cephalalgia : an international journal of headache},
  year={2014},
  volume={34 13},
  pages={1062-9}
}
BACKGROUND Familial hemiplegic migraine (FHM) is a rare monogenic subtype of migraine with aura, characterized by motor auras. The majority of FHM families have mutations in the CACNA1A and ATP1A2 genes; less than 5% of FHM families are explained by mutations in the SCN1A gene. Here we screened two Spanish FHM families for mutations in the FHM genes… CONTINUE READING