Two new pterocarpans and a new pyrone derivative with cytotoxic activities from Ptycholobium contortum (N.E.Br.) Brummitt (Leguminosae): revised NMR assignment of mundulea lactone

  title={Two new pterocarpans and a new pyrone derivative with cytotoxic activities from Ptycholobium contortum (N.E.Br.) Brummitt (Leguminosae): revised NMR assignment of mundulea lactone},
  author={Dominique Ngnintedo and Ghislain Wabo Fotso and Victor Kuete and Fr{\'e}d{\'e}ric Nana and Louis Pergaud Sandjo and Oğuzhan Karaosmanoğlu and H{\"u}lya Sivas and F{\'e}lix Keumedjio and Gilbert Kirsch and Bonaventure T. Ngadjui and Kerstin Andrae-Marobela},
  journal={Chemistry Central Journal},
BackgroundPtycholobium is a genus related to Tephrosia which comprises only three species. Compared to Tephrosia, which has been phytochemically and pharmacologically studied, Ptycholobium species have only few or no reports on their chemical constituents. Moreover, no studies on the cytotoxic activities of its secondary metabolites have been previously documented.ResultsFrom the non polar fractions of the roots bark of Ptycholobium contortum (syn Tephrosia contorta), two new pterocarpans… Expand
Synthesis of Novel Stilbene–Coumarin Derivatives and Antifungal Screening of Monotes kerstingii-Specialized Metabolites Against Fusarium oxysporum
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Cytotoxicity of seputhecarpan D, thonningiol and 12 other phytochemicals from African flora towards human carcinoma cells
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Cytotoxicity of epunctanone and four other phytochemicals isolated from the medicinal plants Garcinia epunctata and Ptycholobium contortum towards multi-factorial drug resistant cancer cells.
  • A. Mbaveng, G. Fotso, +5 authors T. Efferth
  • Chemistry, Medicine
  • Phytomedicine : international journal of phytotherapy and phytopharmacology
  • 2018
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Abstract Two new pterocarpans, seputhecarpan A ( 1 ) and B ( 2 ) and a new isoflavanone seputheisoflavone ( 3 ) were isolated from the roots of Ptycholobium contortum . Seputhecarpan A and B wereExpand
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A Review on the Phytochemistry and Pharmacology of Genus Tephrosia
This review includes the chemical studies on different species mainly the isolation and identification of flavonoids, rotenoids and study of activity of some isolated compounds and also includes diffe-rent pharmacological activities like antioxidant, antimicrobial, anticancer, antiplas-modial, anti-inflammatory, larvicidal and toxicity studies of extracts and fractions. Expand
The biosynthesis of quinones from p-hydroxybenzoic acid in Euglena gracilis var. bacillaris☆
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Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense.
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Two prenylated flavanones from Mundulea suberosa
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