Two new meroterpenoids, penisimplicin A and B, isolated from Penicillium simplicissimum.

@article{Komai2005TwoNM,
  title={Two new meroterpenoids, penisimplicin A and B, isolated from Penicillium simplicissimum.},
  author={Shin-ichirou Komai and Tomoo Hosoe and Takeshi Itabashi and Koohei Nozawa and Kaoru Okada and Galba Maria Campos Takaki and Takashi Yaguchi and Kayoko Takizawa and Kazutaka Fukushima and Ken-ichi Kawai},
  journal={Chemical \& pharmaceutical bulletin},
  year={2005},
  volume={53 9},
  pages={
          1114-7
        }
}
In the course of our research for new antifungal agents, two new meroterpenoids, penisimplicin A (1) and B (2), were isolated from Penicillium simplicissimum. The absolute structures of 1 and 2 were established by spectroscopic and chemical investigation. Penisimplicin A (1) and B (2) are rare examples of D-ring seco-meroterpenoids. Since compounds 1 and 2 showed no antifungal activities, the isolation of the compounds with antifungal activity will be attempted. 

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