Two new forms of gonadotropin-releasing hormone in a protochordate and the evolutionary implications.

@article{Powell1996TwoNF,
  title={Two new forms of gonadotropin-releasing hormone in a protochordate and the evolutionary implications.},
  author={James F F Powell and S M Reska-Skinner and Manish Prakash and Wolfgang K. Fischer and Min Kyun Park and Jean E F Rivier and A. G. Craig and George O. Mackie and Nancy McKeown Sherwood},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 19},
  pages={10461-4}
}
The neuropeptide gonadotropin-releasing hormone (GnRH) is the major regulator of reproduction in vertebrates. Our goal was to determine whether GnRH could be isolated and identified by primary structure in a protochordate and to examine its location by immunocytochemistry. The primary structure of two novel decapeptides from the tunicate Chelyosoma productum (class Ascidiacea) was determined. Both show significant identity with vertebrate GnRH. Tunicate GnRH-I (pGlu-His-Trp-Ser-Asp-Tyr-Phe-Lys… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

Similar Papers

Loading similar papers…