Two new ent-kaurane diterpenes from the stems of Eurya chinensis

@article{Song2018TwoNE,
  title={Two new ent-kaurane diterpenes from the stems of Eurya chinensis},
  author={Jia-ling Song and Yao Yuan and Linghui Nie and Bailin Li and Xu-Bing Qin and Yan Li and Jie-Wei Wu and S. Qiu},
  journal={Journal of Asian Natural Products Research},
  year={2018},
  volume={20},
  pages={962 - 968}
}
Abstract Two new ent-kaurane diterpenes (1–2), together with five known analogs, were isolated from the stems of Eurya chinensis. The structures of new compounds were established by extensive analysis of mass spectrometric and 1D and 2D NMR spectroscopic data. Compound 3 exhibited noticeable anti-inflammatory activity as denoted by inhibiting LPS-induced nitric oxide (NO) production in RAW264.7 cells with an IC50 value of 7.82 μM. Compound 4 showed potent cytotoxic activity against human cancer… Expand

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