Two new cytotoxic tetracyclic tetraterpenoids from the soft coral Sarcophyton tortuosum.

@article{Zeng2004TwoNC,
  title={Two new cytotoxic tetracyclic tetraterpenoids from the soft coral Sarcophyton tortuosum.},
  author={Longmei Zeng and Wen-Jian Lan and Jingyu. Su and Guang-Wen Zhang and Xiao-Long Feng and Yong-Ju Liang and Xiao-Ping Yang},
  journal={Journal of natural products},
  year={2004},
  volume={67 11},
  pages={
          1915-8
        }
}
Two new cytotoxic tetracyclic tetraterpenoids, methyl tortuoate A (1) and methyl tortuoate B (2), along with the known methyl sartortuoate (3) were isolated from the soft coral Sarcophyton tortuosum. The structures of 1 and 2 were established by spectroscopic methods, mainly on the basis of 2D NMR techniques, and were confirmed by single-crystal X-ray diffraction analysis. The cytotoxic activities of these compounds were carried out in vitro on human nasophyringeal carcinoma (CNE-2) and murine… 
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