Two modes of PriA binding to DNA.

  title={Two modes of PriA binding to DNA.},
  author={Pearl Nurse and J Liu and Kenneth J. Marians},
  journal={The Journal of biological chemistry},
  volume={274 35},
The role of PriA, required for the assembly of the phiX174-type primosome on DNA, in cellular DNA replication has been unclear since its discovery. Recent evidence, based on the phenotypes of strains carrying priA null mutations, has led to proposals that the primosome assembly activity of PriA was required to load replication forks at intermediates such as D loops during homologous recombination. McGlynn et al. (McGlynn, P., Al-Deib, A. A., Liu, J., Marians, K. J., and Lloyd, R. G. (1997) J… CONTINUE READING

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