Two models of epileptic spike-and-wave rhythm in rats are differently influenced by ethosuximide.

Abstract

Epileptic afterdischarges induced by electrical stimulation of the sensorimotor cortex as well as minimal metrazol seizures are characterized by EEG spike-and-wave rhythm and nearly the same motor pattern of clonic seizures. The action of ethosuximide on these two models was tested in adult rats with implanted electrodes. Cortical afterdischarges remained… (More)

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Cite this paper

@article{Mars1997TwoMO, title={Two models of epileptic spike-and-wave rhythm in rats are differently influenced by ethosuximide.}, author={P. Mar{\`e}s and Hana Kubov{\'a} and Martina Mockova}, journal={Physiological research}, year={1997}, volume={46 5}, pages={397-402} }