Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase

Abstract

During anaphase identical sister chromatids separate and move towards opposite poles of the mitotic spindle. In the spindle, kinetochore microtubules have their plus ends embedded in the kinetochore and their minus ends at the spindle pole. Two models have been proposed to account for the movement of chromatids during anaphase. In the ‘Pac-Man’ model… (More)
DOI: 10.1038/nature02256

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