Corpus ID: 25366760

Two methods of single-dose ampule opening and their influence upon glass particulate contamination.

@article{Giambrone1991TwoMO,
  title={Two methods of single-dose ampule opening and their influence upon glass particulate contamination.},
  author={A. Giambrone},
  journal={AANA journal},
  year={1991},
  volume={59 3},
  pages={
          225-8
        }
}
Contamination of glass ampules by glass fragments can occur following ampule opening. The intravenous administration of these glass fragments in animal experiments has resulted in insult to the brain, pulmonary, hepatic, renal, and splenic systems of these animals. Thus, it is of clinical importance to determine quantitatively the extent of glass particulate contamination by examining the different methods of glass ampule opening. Twenty, 2-mL single-dose glass ampules were examined for glass… Expand
6 Citations

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