Two major classes in the M protein family in group A streptococci.

  title={Two major classes in the M protein family in group A streptococci.},
  author={Paul W O'Toole and Leisa M Stenberg and Michael Rissler and Gunnar Lindahl},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={89 18},
The M protein family of molecules in the group A streptococcus comprises a number of cell surface proteins that interact with the immune system of the host. One of the proteins in this family is the IgA receptor Arp4, which has C repeats similar to those that characterize the known M proteins. The streptococcal strain expressing Arp4 also expresses a second immunoglobulin-binding protein, Mrp4, which is shown here to be encoded by a gene located immediately upstream of the gene for Arp4. In… CONTINUE READING

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