Two levels of regulation of beta-interferon gene expression in human cells.

@article{Raj1983TwoLO,
  title={Two levels of regulation of beta-interferon gene expression in human cells.},
  author={N. B. Raj and P. M. Pitha},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1983},
  volume={80 13},
  pages={3923-7}
}
We cloned alpha- and beta-interferon cDNA and used them as specific probes to determine the relative levels of interferon mRNA in human fibroblasts cells induced with poly(rI).poly(rC) or Newcastle disease virus to synthesize interferon. Both inducers activated only the beta-interferon gene; however, the half life of beta-interferon mRNA in cells induced… CONTINUE READING