Two intracellular helices of G-protein coupling receptors could generally support oligomerization and coupling with transducers

@article{Parker2010TwoIH,
  title={Two intracellular helices of G-protein coupling receptors could generally support oligomerization and coupling with transducers},
  author={Michael S. Parker and Edwards A. Park and Floyd R. Sallee and Steven L. Parker},
  journal={Amino Acids},
  year={2010},
  volume={40},
  pages={261-268}
}
For many G-protein coupling receptors (GPCRs), the upkeep of receptor dimers could depend on association with functional Gi α subunits. This is known for Y1, Y2 and Y4 neuropeptide Y receptors [presented in the companion paper (Estes et al., Amino Acids, doi: 10.1007/s00726-010-0642-z , 2010)]. Interactions with transducers use mainly intracellular domains… CONTINUE READING