Two highly similar LAEDDTNAQKT and LTDKIGTEI epitopes in G glycoprotein may be useful for effective epitope based vaccine design against pathogenic Henipavirus

@article{Parvege2016TwoHS,
  title={Two highly similar LAEDDTNAQKT and LTDKIGTEI epitopes in G glycoprotein may be useful for effective epitope based vaccine design against pathogenic Henipavirus},
  author={Md. Masud Parvege and Monzilur Rahman and Yead Morshed Nibir and Mohammad Shahnoor Hossain},
  journal={Computational biology and chemistry},
  year={2016},
  volume={61},
  pages={
          270-80
        }
}
Nipah virus and Hendra virus, two members of the genus Henipavirus, are newly emerging zoonotic pathogens which cause acute respiratory illness and severe encephalitis in human. Lack of the effective antiviral therapy endorses the urgency for the development of vaccine against these deadly viruses. In this study, we employed various computational approaches to identify epitopes which has the potential for vaccine development. By analyzing the immune parameters of the conserved sequences of G… CONTINUE READING