Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.

  title={Two genetic variants of CD38 in subjects with autism spectrum disorder and controls.},
  author={Toshio Munesue and Shigeru Yokoyama and Kazuhiko Nakamura and A J Joyce Anitha and Kiyofumi Yamada and Kenshi Hayashi and Tomoya Asaka and Hong-Xiang Liu and Duo Jin and Keita Koizumi and Mohammad Saharul Islam and Jian-Jun Huang and Wen-jie Ma and U Kim and S Z Kim and Keunwan Park and Dongsup Kim and Mitsuru Kikuchi and Yasuki Ono and Hideo Nakatani and Shiro Suda and Taishi Miyachi and Hirokazu Hirai and Alla Salmina and Yu A Pichugina and Andrei A Soumarokov and Nori Takei and Norio Mori and Masatsugu Tsujii and Toshiro Sugiyama and Kunimasa Yagi and Masakazu Yamagishi and Tsukasa Sasaki and Hidenori Yamasue and Nobumasa Kato and Ryota Hashimoto and Masako Taniike and Yutaka Hayashi and Junichiro Hamada and Shioto Suzuki and Akishi Ooi and Mami Noda and Yuko Kamiyama and Mizuho A. Kido and Olga Lopatina and Minako Hashii and Sarwat Amina and Fabio Malavasi and Eric H. Huang and Jiasheng Zhang and Nobuaki Shimizu and Takeo Yoshikawa and Akihiro Matsushima and Yoshio Minabe and Haruhiro Higashida},
  journal={Neuroscience research},
  volume={67 2},
The neurobiological basis of autism spectrum disorder (ASD) remains poorly understood. Given the role of CD38 in social recognition through oxytocin (OT) release, we hypothesized that CD38 may play a role in the etiology of ASD. Here, we first examined the immunohistochemical expression of CD38 in the hypothalamus of post-mortem brains of non-ASD subjects and found that CD38 was colocalized with OT in secretory neurons. In studies of the association between CD38 and autism, we analyzed 10… CONTINUE READING
80 Citations
60 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 80 extracted citations


Publications referenced by this paper.
Showing 1-10 of 60 references

Agenome - wide linkageandassociation scan reveals novel loci for autism

  • A. K. Wermter, I. Kamp-Becker, P. Hesse, G. Schulte-Körne, K. Strauch
  • Nature
  • 2009

Autismgenome - wide copynumber variation reveals ubiquitin and neuronal genes

  • S. G. Gregory, J. J. Connelly, +14 authors M. A. Pericak-Vance
  • Nature
  • 2009
1 Excerpt

Similar Papers

Loading similar papers…