Two forms of death in ageing Caenorhabditis elegans

@inproceedings{Zhao2017TwoFO,
  title={Two forms of death in ageing Caenorhabditis elegans},
  author={Yuan Zhao and Ann F. Gilliat and Matthias Ziehm and Mark Turmaine and Hongyuan Wang and Marina Ezcurra and Chenhao Yang and George Phillips and David McBay and William B. Zhang and Linda Partridge and Zachary Pincus and David Gems},
  booktitle={Nature communications},
  year={2017}
}
Ageing generates senescent pathologies, some of which cause death. Interventions that delay or prevent lethal pathologies will extend lifespan. Here we identify life-limiting pathologies in Caenorhabditis elegans with a necropsy analysis of worms that have died of old age. Our results imply the presence of multiple causes of death. Specifically, we identify two classes of corpse: early deaths with a swollen pharynx (which we call 'P deaths'), and later deaths with an atrophied pharynx (termed… CONTINUE READING

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