Two-electrode voltage clamp.

@article{Guan2013TwoelectrodeVC,
  title={Two-electrode voltage clamp.},
  author={Bingcai Guan and Xing-juan Chen and Hailin Zhang},
  journal={Methods in molecular biology},
  year={2013},
  volume={998},
  pages={79-89}
}
Two-electrode voltage clamp (TEVC) is a conventional electrophysiological technique used to artificially control the membrane potential (V m) of large cells to study the properties of electrogenic membrane proteins, especially ion channels. It makes use of two intracellular electrodes-a voltage electrode as V m sensor and a current electrode for current injection to adjust the V m, thus setting the membrane potential at desired values and recording the membrane current to analyze ion channel… CONTINUE READING
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