Two distinct populations of doublecortin-positive cells in the perilesional zone of cortical infarcts

@inproceedings{Kunze2015TwoDP,
  title={Two distinct populations of doublecortin-positive cells in the perilesional zone of cortical infarcts},
  author={Albrecht Kunze and Alexandra Achilles and Silke Keiner and Otto W. Witte and Christoph Redecker},
  booktitle={BMC Neuroscience},
  year={2015}
}
Recovery following stroke depends on cellular plasticity in the perilesional zone (PZ). Doublecortin (DCX), a protein mainly labeling immature neurons in neurogenic niches is also highly expressed in the vicinity of focal cortical infarcts. Notably, the number of DCX+ cells positively correlates with the recovery of functional deficits after stroke though the nature and origin of these cells remains unclear. In the present study, we aimed to characterize the population of DCX+ cells in the… CONTINUE READING
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