Two distinct modes of myosin assembly and dynamics during epithelial wound closure

@article{Tamada2007TwoDM,
  title={Two distinct modes of myosin assembly and dynamics during epithelial wound closure},
  author={Masako Tamada and Tom{\'a}s Delgado P{\'e}rez and William James Nelson and Michael P. Sheetz},
  journal={The Journal of Cell Biology},
  year={2007},
  volume={176},
  pages={545 - 545}
}
Actomyosin contraction powers the sealing of epithelial sheets during embryogenesis and wound closure; however, the mechanisms are poorly understood. After laser ablation wounding of Madin-Darby canine kidney cell monolayers, we observed distinct steps in wound closure from time-lapse images of myosin distribution during resealing. Immediately upon wounding, actin and myosin II regulatory light chain accumulated at two locations: (1) in a ring adjacent to the tight junction that circumscribed… CONTINUE READING

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Wound healing recapitulates morphogenesis in Drosophila embryos

  • Nature Cell Biology
  • 2002
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