Two distinct layer-specific dynamics of cortical ensembles during learning of a motor task

@article{Masamizu2014TwoDL,
  title={Two distinct layer-specific dynamics of cortical ensembles during learning of a motor task},
  author={Yoshito Masamizu and Yasuhiro Tanaka and Yasuyo H Tanaka and Riichiro Hira and Fuki Ohkubo and Kazuo Kitamura and Yoshikazu Isomura and Takashi Okada and Masanori Matsuzaki},
  journal={Nature Neuroscience},
  year={2014},
  volume={17},
  pages={987-994}
}
The primary motor cortex (M1) possesses two intermediate layers upstream of the motor-output layer: layer 2/3 (L2/3) and layer 5a (L5a). Although repetitive training often improves motor performance and movement coding by M1 neuronal ensembles, it is unclear how neuronal activities in L2/3 and L5a are reorganized during motor task learning. We conducted two-photon calcium imaging in mouse M1 during 14 training sessions of a self-initiated lever-pull task. In L2/3, the accuracy of neuronal… CONTINUE READING
42 Citations
61 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 42 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 61 references

Similar Papers

Loading similar papers…