Two distinct gene subfamilies within the family of cysteine protease genes.

@article{Karrer1993TwoDG,
  title={Two distinct gene subfamilies within the family of cysteine protease genes.},
  author={K. M. Karrer and S L Peiffer and M E DiTomas},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1993},
  volume={90 7},
  pages={3063-7}
}
A cDNA clone for a physiologically regulated Tetrahymena cysteine protease gene was sequenced. The nucleotide sequence predicts that the clone encodes a 336-amino acid protein composed of a 19-residue N-terminal signal sequence followed by a 107-residue propeptide and a 210-residue mature protein. Comparison of the deduced amino acid sequence of the protein with those of other cysteine proteases revealed a highly conserved interspersed amino acid motif in the propeptide region of the protein… CONTINUE READING
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