Two distinct O-methyltransferases in aflatoxin biosynthesis.

@article{Yabe1989TwoDO,
  title={Two distinct O-methyltransferases in aflatoxin biosynthesis.},
  author={Kimiko Yabe and Yasuke Ando and Jun–ichi Hashimoto and Takashi Hamasaki},
  journal={Applied and environmental microbiology},
  year={1989},
  volume={55 9},
  pages={
          2172-7
        }
}
The substances belonging to the sterigmatocystin group bear a close structural relationship to aflatoxins. When demethylsterigmatocystin (DMST) was fed to Aspergillus parasiticus NIAH-26, which endogenously produces neither aflatoxins nor precursors in YES medium, aflatoxins B1 and G1 were produced. When dihydrodemethylsterigmatocystin (DHDMST) was fed to this mutant, aflatoxins B2 and G2 were produced. Results of the cell-free experiment with S-adenosyl-[methyl-3H]methionine showed that first… CONTINUE READING

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