Two discrete regions of deletion at 7q in uterine leiomyomas.

  title={Two discrete regions of deletion at 7q in uterine leiomyomas.},
  author={Chandramohan S Ishwad and Robert E. Ferrell and Kathleen M. Hanley and Jayant R Davare and Anna Maria Meloni and Avery A. Sandberg and Urvashi Surti},
  journal={Genes, chromosomes & cancer},
  volume={19 3},
This study further defines the region of consistent deletion of chromosome 7 in uterine leiomyomas. We have examined 74 leiomyomas for allelic loss of markers spanning the 7q22 region defined by markers D7S518 and D7S471. Forty tumors with cytogenetically defined 7q deletions, twenty-nine tumors without cytogenetically visible 7q deletions, and five tumors with no cytogenetic information were examined for allelic loss of D7S518, D7S666, D7S515, D7S658, D7S496, D7S692, and D7S471. Loss of… CONTINUE READING
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