Two-dimensional echocardiography with a 15-MHz transducer is a promising alternative for in vivo measurement of left ventricular mass in mice.

@article{Youn1999TwodimensionalEW,
  title={Two-dimensional echocardiography with a 15-MHz transducer is a promising alternative for in vivo measurement of left ventricular mass in mice.},
  author={Hyun Ju Youn and Gregg D. Rokosh and Steven J Lester and Paul Simpson and Nelson B. Schiller and E Terence Foster},
  journal={Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography},
  year={1999},
  volume={12 1},
  pages={70-5}
}
Murine models of left ventricular (LV) hypertrophy recently have been developed. We tested the accuracy of 2-dimensional (2D) echocardiographic measurement of LV mass with high-frequency imaging in mice. Ten anesthetized mice (weight 20 to 31 g, aged 1 to 5 months) were examined with a 15-MHz transthoracic linear-array transducer. End-diastolic myocardial area (A)(epicardial - endocardial) from the parasternal short-axis view at the midpapillary level and LV length (L) from the parasternal long… CONTINUE READING

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