Two dimensional diffusion of small molecules on protein surfaces: an EPR study of the restricted translational diffusion of protein-bound spin labels

@article{Steinhoff1991TwoDD,
  title={Two dimensional diffusion of small molecules on protein surfaces: an EPR study of the restricted translational diffusion of protein-bound spin labels},
  author={Heinz -J{\"u}rgen Steinhoff and Olaf Dombrowsky and Christine Karim and Christoph Schneiderhahn},
  journal={European Biophysics Journal},
  year={1991},
  volume={20},
  pages={293-303}
}
Heisenberg spin exchange rates and dipole-dipole spin lattice relaxation rates for deuterated 14N- and 15N-spin labels bound selectively to the histidine His15 and to the lysines Lys13, 96, 97 of the lysozyme molecule have been determined with the aid of electron spin resonance spectroscopy. The results can be interpreted in terms of a two dimensional translational diffusion of the nitroxide tips of the spin labels along the protein surface within restricted surface areas. The spin labels are… CONTINUE READING