Two-dimensional crystallization of the mouse serotonin 5-HT3A receptor.

Abstract

The mouse serotonin 5-HT3A receptor is a homo-pentameric ligand-gated ion channel (pLGIC) mediating fast excitatory neurotransmission in the central nervous system. The molecular mechanism of ion permeation of 5-HT3A receptors triggered by the neurotransmitter serotonin is not yet fully understood. The recent X-ray structure of the mouse serotonin 5-HT3A… (More)
DOI: 10.1016/j.micron.2016.10.004

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