Two different approaches for pharmacokinetic modeling of exhaled drug concentrations

@inproceedings{Kreuer2014TwoDA,
  title={Two different approaches for pharmacokinetic modeling of exhaled drug concentrations},
  author={Sascha Kreuer and A. Hauschild and Tobias Fink and J{\"o}rg Ingo Baumbach and Sasidhar Maddula and Th. Volk},
  booktitle={Scientific reports},
  year={2014}
}
Online measurement of drug concentrations in patient's breath is a promising approach for individualized dosage. A direct transfer from breath- to blood-concentrations is not possible. Measured exhaled concentrations are following the blood-concentration with a delay in non-steady-state situations. Therefore, it is necessary to integrate the breath… CONTINUE READING