Two components of transmitter release in retinal bipolar cells: exocytosis and mobilization of synaptic vesicles.

@article{Sakaba1997TwoCO,
  title={Two components of transmitter release in retinal bipolar cells: exocytosis and mobilization of synaptic vesicles.},
  author={Takeshi Sakaba and Masao Tachibana and Ko Matsui and Natsumi Minami},
  journal={Neuroscience research},
  year={1997},
  volume={27 4},
  pages={357-70}
}
Ca2+-transmitter release coupling was examined using bipolar cells with large presynaptic terminals dissociated from the goldfish retina. Presynaptic Ca2+ current (I(Ca)) was recorded under the whole-cell voltage clamp. Release of excitatory amino acid transmitter was simultaneously monitored as the current through N-methyl-D-asperate (NMDA) receptors of reporter cells or as the membrane capacitance (C(m)) change associated with exocytosis. When I(Ca) was activated by a long depolarizing pulse… CONTINUE READING

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