Two components of potassium current activated by depolarization of single smooth muscle cells from the rabbit portal vein.

@article{Beech1989TwoCO,
  title={Two components of potassium current activated by depolarization of single smooth muscle cells from the rabbit portal vein.},
  author={David J Beech and Thomas B. Bolton},
  journal={The Journal of physiology},
  year={1989},
  volume={418},
  pages={293-309}
}
1. Using the patch-clamp technique at 20-23 degrees C membrane currents were recorded from single smooth muscle cells enzymatically isolated from the rabbit portal vein. Single-channel currents were observed in outside-out patches excised from these. 2. Outward current elicited upon depolarization from -70 mV was not activated as a result of Ca2+ influx. It could be divided into two components: an inactivating, 4-aminopyridine- and phencyclidine-sensitive low-noise current (IdK), and a non… CONTINUE READING