Two-component systems and toxinogenesis regulation in Clostridium botulinum.

@article{Connan2015TwocomponentSA,
  title={Two-component systems and toxinogenesis regulation in Clostridium botulinum.},
  author={Chlo{\'e} Connan and Michel Robert Popoff},
  journal={Research in microbiology},
  year={2015},
  volume={166 4},
  pages={332-43}
}
Botulinum neurotoxins (BoNTs) are the most potent toxins ever known. They are mostly produced by Clostridium botulinum but also by other clostridia. BoNTs associate with non-toxic proteins (ANTPs) to form complexes of various sizes. Toxin production is highly regulated through complex networks of regulatory systems involving an alternative sigma factor… CONTINUE READING