Two-component response regulators of Vibrio fischeri: identification, mutagenesis, and characterization.

@article{Hussa2007TwocomponentRR,
  title={Two-component response regulators of Vibrio fischeri: identification, mutagenesis, and characterization.},
  author={Elizabeth A Hussa and Therese M O'Shea and Cynthia L. Darnell and Edward G. Ruby and Karen L Visick},
  journal={Journal of bacteriology},
  year={2007},
  volume={189 16},
  pages={5825-38}
}
Two-component signal transduction systems are utilized by prokaryotic and eukaryotic cells to sense and respond to environmental stimuli, both to maintain homeostasis and to rapidly adapt to changing conditions. Studies have begun to emerge that utilize a large-scale mutagenesis approach to analyzing these systems in prokaryotic organisms. Due to the recent availability of its genome sequence, such a global approach is now possible for the marine bioluminescent bacterium Vibrio fischeri, which… CONTINUE READING