Two common mitochondrial DNA polymorphisms are highly associated with migraine headache and cyclic vomiting syndrome.

@article{Zaki2009TwoCM,
  title={Two common mitochondrial DNA polymorphisms are highly associated with migraine headache and cyclic vomiting syndrome.},
  author={Essam A. Zaki and Tobias Freilinger and Thomas Klopstock and Erin E. Baldwin and K R U Heisner and Kathleen O Adams and Martin Dichgans and Stefan Wagler and Richard G. Boles},
  journal={Cephalalgia : an international journal of headache},
  year={2009},
  volume={29 7},
  pages={719-28}
}
Mitochondrial dysfunction is a hypothesized component in the multifactorial pathogenesis of migraine without aura (MoA, 'common migraine') and the related condition of cyclic vomiting syndrome (CVS). In this study, the entire mitochondrial genome was sequenced in 20 haplogroup-H CVS patients, a subject group studied because of greater genotypic and… CONTINUE READING