Two common mild analgesics have no effect on general endocrine mediated endpoints in zebrafish (Danio rerio).

Abstract

Mild analgesics such as acetylsalicylic acid (ASA) and acetaminophen (APAP) exert their pain-relieving effect in humans by inhibition of prostaglandin synthesis. Prostaglandins play key roles in developmental and reproductive processes in vertebrates, and in recent years, it has been suggested that weak analgesics might also act as endocrine disrupters. In… (More)
DOI: 10.1016/j.cbpc.2017.11.009

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