Two classes of new peptaibols are synthesized by a single non-ribosomal peptide synthetase of Trichoderma virens.

@article{Mukherjee2011TwoCO,
  title={Two classes of new peptaibols are synthesized by a single non-ribosomal peptide synthetase of Trichoderma virens.},
  author={Prasun Kumar Mukherjee and Aric Wiest and Nicolas Ruiz and Andrew Keightley and M. Eugenia Mor{\'a}n-Diez and Kevin McCluskey and Yves François Pouchus and Charles M. Kenerley},
  journal={The Journal of biological chemistry},
  year={2011},
  volume={286 6},
  pages={4544-54}
}
Peptaibols are a group of small peptides having a high α-aminoisobutyric acid (Aib) content and produced by filamentous fungi, especially by the members of the genus Trichoderma (anamorph Hypocrea). These antibiotics are economically important for their anti-microbial and anti-cancer properties as well as ability to induce systemic resistance in plants against microbial invasion. In this study we present sequences of two classes (11-residue and 14-residue) of peptaibols produced by the… CONTINUE READING

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