Two cellular and subcellular locations for the peripheral-type benzodiazepine receptor in rat liver.

Abstract

Determination of ligand binding properties of the peripheral benzodiazepine receptor (PBBS) in liver, in hepatocytes, and in nonparenchymal cells demonstrated the presence of receptor-specific high-affinity binding in both hepatocyte and nonhepatocyte cells. Density gradient centrifugation showed that the high-affinity receptor in hepatocytes was localised… (More)

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