Two cases of fatal Pneumocystis jirovecii pneumonia as a complication of tacrolimus therapy in ulcerative colitis--a need for prophylaxis.

Abstract

Here we report 2 cases of fatal Pneumocystis jirovecii pneumonia in patients with severe ulcerative colitis receiving combination immunosuppression including tacrolimus. We discuss the necessity of a P. jirovecii prophylaxis especially in elderly patients according to the European evidence-based consensus on the prevention and management of opportunistic infections in inflammatory bowel disease.

DOI: 10.1016/j.crohns.2010.05.004

Cite this paper

@article{Escher2010TwoCO, title={Two cases of fatal Pneumocystis jirovecii pneumonia as a complication of tacrolimus therapy in ulcerative colitis--a need for prophylaxis.}, author={Markus Escher and Eduard Friedrich Stange and Klaus Richard Herrlinger}, journal={Journal of Crohn's & colitis}, year={2010}, volume={4 5}, pages={606-9} }