Two cases of asymptomatic HBV “vaccine breakthrough” infection detected in blood donors screened for HBV DNA

  title={Two cases of asymptomatic HBV “vaccine breakthrough” infection detected in blood donors screened for HBV DNA},
  author={Clive R. Seed and Ngaire T Jones and Anne M Pickworth and Wendy J. Graham},
  journal={Medical Journal of Australia},
A 35-year-old male first-time blood donor who donated in June 2011 tested positive for HBV (hepatitis B virus) DNA (Box). DNA sequencing analysis identified HBV genotype E. The only other HBV marker present was anti-HBs (antibodies to HBV surface antigen), attributable to a full course of vaccination in 2003–2004. A followup interview identified heterosexual contact with a new partner as the likely source of infection. HBsAg (HBV surface antigen) remained undetectable throughout the 90-day… 
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