Two calcium channels in basolateral membranes of rabbit ileal epithelial cells.

@article{Homaidan1989TwoCC,
  title={Two calcium channels in basolateral membranes of rabbit ileal epithelial cells.},
  author={Fadia R. Homaidan and Mark Donowitz and Gregory A. Weiland and Geoffrey W. G. Sharp},
  journal={The American journal of physiology},
  year={1989},
  volume={257 1 Pt 1},
  pages={G86-93}
}
The actions of three different types of calcium channel blockers on short-circuit current (Isc) in rabbit ileum were studied. These included the phenylalkylamines, verapamil and (l)-desmethoxyverapamil (D888); the dihydropyridines, nifedipine and nitrendipine; and the benzothiazepine, diltiazem. All of the drugs decreased Isc, a change associated with increased Na and Cl absorption. Verapamil and D888 had the largest effects. The dihydropyridine, BAY K 8644, a calcium channel activator… CONTINUE READING

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