Two bioactive saponins from Albizia subdimidiata from the Suriname rainforest.

@article{AbdelKader2001TwoBS,
  title={Two bioactive saponins from Albizia subdimidiata from the Suriname rainforest.},
  author={Maged. S. Abdel-Kader and Jeannine M Hoch and John Joseph Berger and Richard J. Evans and Sylvain G. Razafimandimbison and Jan H. Wisse and Stephen W. Mamber and James M. Dalton and David G I Kingston},
  journal={Journal of natural products},
  year={2001},
  volume={64 4},
  pages={
          536-9
        }
}
Bioassay-guided fractionation of a methanol extract of Albizia subdimidiata using the engineered yeast strains 1138, 1140, 1353, and Sc7 of Saccharomyces cerevisiae as the bioassay tool resulted in the isolation of the two active saponins 1 and 2; one of these, albiziatrioside A (1), is described for the first time. The structures of 1 and 2 were established on the basis of HRMS, 1D and 2D NMR spectral data, and GC--MS analysis of the sugar units. Both isolated compounds showed significant… CONTINUE READING
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