Two aspects of the excitatory influence of histamine on hippocampal neurons in guinea pigs.


The effect of histamine (Hi) on CA3 pyramidal cells in guinea pig hippocampal slices was studied by means of intracellular recordings in association with electrical stimulation to the mossy fibers of granular cells. The amplitude of EPSPs and spikes was augmented significantly by Hi at concentrations of 10(-7) to 10(-6) M. The stimulatory effect of Hi was… (More)


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