Two SP-C genes encoding human pulmonary surfactant proteolipid.

@article{Glasser1988TwoSG,
  title={Two SP-C genes encoding human pulmonary surfactant proteolipid.},
  author={Stephan W. Glasser and Thomas R. Korfhagen and Charles Perme and Tami J. Pilot-Matias and Stefan Kister and Jeffrey A. Whitsett},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 21},
  pages={
          10326-31
        }
}
Human pulmonary surfactant proteolipid of Mr = 5,000, now termed surfactant protein C (SP-C), is produced by proteolytic processing of an Mr = 22,000 precursor. The active hydrophobic peptide imparts surface active properties to pulmonary surfactant phospholipids. We have determined the entire nucleotide sequence of two distinct genes encoding SP-C from a genomic library prepared from human leukocytes. SP-C genes were encoded by approximately 3.0 kilobase pairs of DNA containing six exons and… CONTINUE READING

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Pedintr . Acknowkdgments - We gratefully acknowledge the assistance of Biochem

  • J. A. Whitsett, R. H. Notter, +4 authors T. E. Weaver
  • 1986

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