Two-Pulse Endosomal Stimulation of Receptor Tyrosine Kinases Induces Cell Proliferation.

Abstract

Signals transduced from ligand-activated receptor tyrosine kinases (RTKs) lead to a diverse array of biological outcomes, such as cell proliferation. Strict regulation of RTK activity is therefore necessary to prevent aberrancies in cell signaling that can lead to diseases such as cancer. RTKs are activated at the plasma membrane (PM) upon ligand binding… (More)
DOI: 10.1007/978-1-4939-7219-7_9

Topics

Cite this paper

@article{Pennock2017TwoPulseES, title={Two-Pulse Endosomal Stimulation of Receptor Tyrosine Kinases Induces Cell Proliferation.}, author={Steven D Pennock and Sukhmani Billing and Zhixiang Wang and Yi Wang}, journal={Methods in molecular biology}, year={2017}, volume={1652}, pages={127-133} }