Two-Partner Secretion: Combining Efficiency and Simplicity in the Secretion of Large Proteins for Bacteria-Host and Bacteria-Bacteria Interactions

@inproceedings{Gurin2017TwoPartnerSC,
  title={Two-Partner Secretion: Combining Efficiency and Simplicity in the Secretion of Large Proteins for Bacteria-Host and Bacteria-Bacteria Interactions},
  author={J{\'e}r{\'e}my Gu{\'e}rin and Sarah Bigot and Robert H. Schneider and Susan K Buchanan and Françoise Jacob-Dubuisson},
  booktitle={Front. Cell. Infect. Microbiol.},
  year={2017}
}
Initially identified in pathogenic Gram-negative bacteria, the two-partner secretion (TPS) pathway, also known as Type Vb secretion, mediates the translocation across the outer membrane of large effector proteins involved in interactions between these pathogens and their hosts. More recently, distinct TPS systems have been shown to secrete toxic effector domains that participate in inter-bacterial competition or cooperation. The effects of these systems are based on kin vs. non-kin molecular… CONTINUE READING
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  • Front. Microbiol.
  • 2019
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