Two New Sarasinosides from the Sponge Melophlus Sarasinorum

  title={Two New Sarasinosides from the Sponge Melophlus Sarasinorum},
  author={Elena A. Santalova and Vladimir Denisenko and Pavel S. Dmitrenok and Dmitrii V. Berdyshev and Valentin A Stonik},
  journal={Natural Product Communications},
Two new 30-norlanostane-type oligoglycosides (6, 7) along with five known sarasinosides A1 (1), A2 (2), A3 (3), M (4), L (5) were isolated from the ethanol extract of the Australian sponge Melophlus sarasinorum. The skeleton of new sarasinoside A4 (6) possesses a rare 8α,9α-oxido-8,9-seco-moiety. Sarasinoside A5 (7) proved to be a 9-deoxy-congener of the previously described sarasinoside L (5). Compounds 1–7 have identical pentasaccharide chains and differ in the aglycone portions. The… 

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