Two New Hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and Cytotoxic Activity of Aggregatin D

@article{Verdan2015TwoNH,
  title={Two New Hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and Cytotoxic Activity of Aggregatin D},
  author={Maria Helena Verdan and Lauro Mera de Souza and Jo{\~a}o Ernesto de Carvalho and D{\'e}bora B. Vendramini Costa and Marcos Jos{\'e} Salvador and Andersson Barison and Maria {\'E}lida Alves Stefanello},
  journal={Chemistry \& Biodiversity},
  year={2015},
  volume={12}
}
Two new hydronaphthoquinones, aggregatins E and F (1 and 2, resp.) were isolated from the tubers of Sinningia aggregata (Ker‐Gawl.) Wiehler (Gesneriaceae), along with twelve known compounds aggregatin D (3), tectoquinone (4), 1‐hydroxy‐2‐methylanthraquinone (5), icosyl ferulate (6), pustuline (7), 1,6‐dihydroxy‐2‐methylanthranquinone (8), 6‐hydroxy‐2‐methylanthraquinone (9), 7‐hydroxy‐2‐methylanthraquinone (10), tyrosol (11), halleridone (12), calceolarioside B (13), and cornoside (14). All… 
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11 Citations

11 Citations

Chemical constituents from Paliavana tenuiflora Mansf. (Gesneriaceae)

Naphthochromenes and Related Constituents from the Tubers of Sinningia allagophylla.

6-Methoxy-7,8-benzocoumarin (6) has been isolated for the first time from a natural source.

Naphthoquinones of Sinningia reitzii and Anti-inflammatory/Antinociceptive Activities of 8-Hydroxydehydrodunnione.

Results suggest that this new naphthoquinone exhibits important anti-inflammatory and antinociceptive activities, which is dissimilar to that of most known analgesics.

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Two New Hydronaphthoquinones from Sinningia aggregata (Gesneriaceae) and Cytotoxic Activity of Aggregatin D.

Two new hydronaphthoquinones, aggregatins E (Ia) and F (Ib), along with twelve known compounds including cytotoxic aggregation D are isolated and structure elucidation are revealed.

The ancient Thracian endemic plant Haberlea rhodopensis Friv. And related species: A review.

Hypoglycemic Activity of Aqueous Extract of Latex from Hancornia speciosa Gomes: A Study in Zebrafish and In Silico

The results show a hypoglycemic activity of the extract in vivo, with no apparent toxicity, and computational studies suggest this could be at least partially due to the presence of bornesitol, since inositols can interact with carbohydrates’ enzymes.

Two new secondary metabolites from Oreocharis auricula and their chemotaxonomic significance

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